You may have used more symbols than you are allowed with your subscription. Check Program menu > System Log > Symbol Usage for a clue to where you have used up the symbols. Reduce the usage accordingly.
Next, to reset the symbol count on the eSignal Data Manager, close all other programs connected to eSignal Data Manager, then close eSignal Data Manager manually. NeoTicker® will then automatically re-launch and reconnects to eSignal Data Manager.